Restorative and health-Enhancing Sleep Time (REST)

The Advanced Research Projects Agency for Health (ARPA-H) seeks proposals for the Restorative & health-Enhancing Sleep Time (REST) program, a bold effort to transform how poor sleep is measured and treated by enabling objective, home-based, closed-loop technologies that detect health-relevant sleep microstructures and respond to them in real time. If successful, REST will establish the technical foundation for a new generation of sleep health technologies that are objective, personalized, and capable of improving long-term health outcomes at scale. 6/16: Amendment 1 updates links within the ISO 6/18: Amendment 2 adds Section 6.5 Questions and Answers 6/24: Amendment 3 makes various edits for clarification in Sections 1-3. 7/7: Amendment 4 modifies the table in Section 3.2.1 TA1 Success Metrics. 7/16: Amendment 5 modifies additional text within the table in Section 3.2.1 TA1 Success Metrics. 8/10: Amendment 6 modifies the solicitation by breaking the Solution Summary, Proposal and Pitch into distinct categories. Solution Summaries will be reviewed on an encourage/discourage basis; Proposals will be evaluated on an invite/not invited basis; Pitches will be evaluated on a selected for negotiation/not selected basis. 8/11: Amendment 7 modifies Section 3.3 Key Program Milestones table. Changes made in Amendment 6 remain in red text to highlight important changes to solicitation process. 9/14: Amendment 8 modifies Section 4.4 Proposal Requirements and reactivates solicitation until proposal due date. 9/15: Amendment 9 adds REST Proposal Template folder as an attachment to the solicitation. 9/21: Amendment 10 revises REST Proposal Template document "REST_APPENDIX B.0_Proposal Format and Instructions". 10/2: Amendment 11 revises section 4.5 of the ISO, adds expected dates of pitch sessions, and revises "REST_APPENDIX B.0_Proposal Format and Instructions". Additionally, this amendment removed the cost breakout by task tab from both Cost Proposal spreadsheets. No substantive