Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS)

13 NOV: Amendment 1 provides minor revisions to the ISO (see orange text). The link to the SURPASS webinar has also been added to this posting. 30 SEP: The Advanced Research Projects Agency for Health (ARPA-H) posts this solicitation in support of its Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) Program. ARPA-H anticipates multiple Other Transaction Agreement awards will result from this opportunity. Interested parties are invited to review the attached Solicitation (ARPA-H-SOL-26-164) and associated attachments. As detailed in Special Notice ARPA-H-SN-26-164, ARPA-H will host an informational webinar on 15 OCT 2026 and a 2-day Proposers’ Day on 6 and 9 NOV 2026 in support of SURPASS. All questions related to SURPASS should be submitted to SURPASS@ARPA-H.GOV.