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Confocal Super Resolution Microscope

BROOKHAVEN NATL LAB -DOE CONTRACTOR

This is for the procurement of a Confocal Super Resolution Microscope (SRM) at Brookhaven National Laboratory. The SRM instrument should provide true confocal point scanning with a tunable white light laser excitation source of visible range capable of simultaneous multi-line operation with independent intensity control and rapid microsecond-scale switching between excitation regime, broadband spectral detection in the range approximately 400–850 nm, with multiple independently configurable detection channels, FLIM/FCS functionality, and analytical tools enabling functional parameter mapping and FRET. Super-resolution performance should include both 2D and 3D STED nanoscopy across the visible spectrum, with possibility to acquire super-resolution imaging at ~30 nm lateral resolution. The instrument should operate within a unified software environment supporting automated calibration, lifetime fitting, super-resolution reconstruction, and compatibility with external analysis platforms.

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